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Статья
Coronavirus disease (COVID-19) and disseminated intravascular coagulation [Коронавирусная инфекция (COVID-19) и синдром диссеминированного внутрисосудистого свертывания]
2021
COVID-19 is an infectious disease caused by the beta-coronavirus SARS-CoV-2 that in 2020 has spread worldwide. In most severe patients, the clinical picture begins with respiratory failure further deteriorating up to multiple organ failure. Development of coagulopathy is the most adverse prognostic. Analyzing currently available clinical data revealed that 71.4 % and 0.6 % of survivors and fatal cases, respectively, demonstrated signs of overt disseminated intravascular coagulation (DIC). Monitoring D-dimer level, prothrombin time, platelet count and fibrinogen content is important for determining indications for treatment and hospitalization in COVID-19 patients. In case such parameters deteriorate, a more pro-active “aggressive” intensive care should be applied. Low molecular weight heparin (LMWH) should be administered to all patients with diagnosed COVID-19 infection (including non-critical patients) requiring hospitalization, but having no contraindications to LMWH. © 2020 Moscow Polytechnic University. All rights reserved.
Цитирование
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Версии
- 1. Version of Record от 2021-04-27
Метаданные
Название журнала
- Obstetrics, Gynecology and Reproduction
Том
- 14
Выпуск
- 2
Страницы
- 123-131
Ключевые слова
- D dimer; fibrinogen; low molecular weight heparin; anticoagulant therapy; Article; clinical feature; coronavirus disease 2019; disseminated intravascular clotting; hospitalization; human; intensive care; laboratory test; medical history; multiple organ failure; pathophysiology; platelet count; prognosis; prothrombin time; Severe acute respiratory syndrome coronavirus 2
Издатель
- IRBIS LLC
Тип документа
- journal article
Тип лицензии Creative Commons
- CC
Правовой статус документа
- Свободная лицензия
Источник
- scopus
