Coronavirus infection (COVID-19) is an acute infectious disease caused by a new strain of the virus of the genus coronavirus SARS-CoV-2 with the aerosol-droplet and contact-household transmission mechanism; patogenetically local and systemic inflammatory process, hyperactive impulsive cascade, endotheliopathy, hypoxia, leading to the development of micro – and microthrombosis; it occurs from asymptomatic to clinically significant forms of intoxication, vascular lesions, lungs, heart, kidneys, and GI tract with risk of complications (ARF, ARDS, sepsis, shock, multiple organ dysfunction SYNDROME, pulmonary embolism). Currently, there are few data on the course of this disease in patients undergoing treatment with program hemodialysis, as well as methods of specific treatment of this group of patients. The article describes the case of the first patient in the Clinical Infectious Hospital named after S.P. Botkin with end-stage chronic kidney disease corrected by program hemodialysis, who had a COVID-19. © 2020 Interregional public organization Association of infectious disease specialists of Saint-Petersburg and Leningrad region (IPO AIDSSPbR). All rights reserved.