Статья

A fiber optic-nanophotonic approach to the detection of antibodies and viral particles of COVID-19

N. Rajil, A. Sokolov, Z. Yi, G. Adams, G. Agarwal, V. Belousov, R. Brick, K. Chapin, J. Cirillo, V. Deckert, S. Delfan, S. Esmaeili, A. Fernández-González, E. Fry, Z. Han, P. Hemmer, G. Kattawar, M. Kim, M. Lee, C. Lu, J. Mogford, B. Neuman, J. Pan, T. Peng, V. Poor, S. Scully, Y. Shih, S. Suckewer, A. Svidzinsky, A. Verhoef, D. Wang, K. Wang, L. Yang, A. Zheltikov, S. Zhu, S. Zubairy, M. Scully,
2021

Dr. Deborah Birx, the White House Coronavirus Task Force coordinator, told NBC News on "Meet the Press"that "[T]he U.S. needs a 'breakthrough' in coronavirus testing to help screen Americans and get a more accurate picture of the virus' spread."We have been involved with biopathogen detection since the 2001 anthrax attacks and were the first to detect anthrax in real-time. A variation on the laser spectroscopic techniques we developed for the rapid detection of anthrax can be applied to detect the Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-CoV-2 virus). In addition to detecting a single virus, this technique allows us to read its surface protein structure. In particular, we have been conducting research based on a variety of quantum optical approaches aimed at improving our ability to detect Corona Virus Disease-2019 (COVID-19) viral infection. Indeed, the detection of a small concentration of antibodies, after an infection has passed, is a challenging problem. Likewise, the early detection of disease, even before a detectible antibody population has been established, is very important. Our team is researching both aspects of this problem. The paper is written to stimulate the interest of both physical and biological scientists in this important problem. It is thus written as a combination of tutorial (review) and future work (preview). We join Prof. Federico Capasso and Editor Dennis Couwenberg in expressing our appreciation to all those working so heroically on all aspects of the COVID-19 problem. And we thank Drs. Capasso and Couwenberg for their invitation to write this paper. © 2020 Navid Rajil et al., published by De Gruyter, Berlin/Boston 2020.

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  • 1. Version of Record от 2021-04-27

Метаданные

Об авторах
  • N. Rajil
    Texas A and M University, College Station, TX 77843, United States
  • A. Sokolov
    Baylor University, Waco, TX 76798, United States
  • Z. Yi
    Friedrich Schiller University, Jena, 07743, Germany
  • G. Adams
    Princeton University, Princeton, NJ 08544, United States
  • G. Agarwal
    Texas A and M University System, College Station, TX 77840, United States
  • V. Belousov
    Collins Aerospace, Richardson, TX 75082, United States
  • R. Brick
    University of Science and Technology of China, Hefei, Anhui, 230026, China
  • K. Chapin
    University of Maryland, 1000 Hilltop Circle Baltimore County, Baltimore, MD 21250, United States
  • J. Cirillo
    Zhejiang University, 38 Zheda Rd, Hangzhou, 310027, China
  • V. Deckert
    Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, 117997, Russian Federation
  • S. Delfan
    Pirogov Russian National Research Medical University, Moscow, 117997, Russian Federation
  • S. Esmaeili
    Federal Center of Brain Research and Neurotechnologies, Federal Medical Biological Agency, Moscow, 117997, Russian Federation
  • A. Fernández-González
    Washington University, St. Louis, MO 63130, United States
  • E. Fry
    International Laser Center, Moscow State University, Moscow, 119992, Russian Federation
  • Z. Han
    Texas A and M University, Texarkana, TX 75503, United States
  • P. Hemmer
    Zavoisky Physical-Technical Institute, Kazan, 420029, Russian Federation
  • G. Kattawar
    Russian Quantum Center, Skolkovo, Moscow Region, 143025, Russian Federation
  • M. Kim
    Leibniz Institute of Photonic Technology, Jena, 07745, Germany
  • M. Lee
  • C. Lu
  • J. Mogford
  • B. Neuman
  • J. Pan
  • T. Peng
  • V. Poor
  • S. Scully
  • Y. Shih
  • S. Suckewer
  • A. Svidzinsky
  • A. Verhoef
  • D. Wang
  • K. Wang
  • L. Yang
  • A. Zheltikov
  • S. Zhu
  • S. Zubairy
  • M. Scully
Название журнала
  • Nanophotonics
Том
  • 10
Выпуск
  • 1
Страницы
  • 235-246
Ключевые слова
  • Antibodies; Chemical detection; Viruses; Laser-spectroscopic technique; Rapid detection; Severe acute respiratory syndrome; Small concentration; Surface proteins; Viral infections; Viral particles; Virus disease; Diseases
Издатель
  • De Gruyter Open Ltd
Тип документа
  • journal article
Тип лицензии Creative Commons
  • CC
Правовой статус документа
  • Свободная лицензия
Источник
  • scopus