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Статья
COVID-19 in solid organ transplant recipients: Initial report from national multicenter observational study «rokkor-recipient» [ОСОБеННОСти КлиНичеСКОГО течеНиЯ КОрОНАВирУСНОЙ иНФеКЦии cOvid-19 У реЦиПиеНтОВ СердЦА, ПОчКи, ПечеНи: ПерВые реЗУлЬтАты НАЦиОНАлЬНОГО МНОГОЦеНтрОВОГО НАБлЮдАтелЬНОГО иССледОВАНиЯ «рОККОр-реЦиПиеНт»]
2021
We herein present our initial report from «ROKKOR-recipient», a national multicenter observational study. The prevalence, risk factors, clinical manifestations and outcomes of the novel coronavirus disease 2019 (COVID-19) in solid organ transplant recipients receiving immunosuppressive therapy were investigated. The study enrolled 251 COVID-19 patients (220 kidney recipients, 7 liver recipients, 1 liver-kidney recipient, and 23 heart recipients). The subjects came from 20 regions in Russia. The symptoms, clinical presentation, imaging and lab test results, therapy and outcomes of COVID-19 were described. It was established that solid organ transplant recipients with COVID-19 have a higher risk of developing adverse events. Predictors of adverse events include associated cardiovascular diseases, pulmonary diseases, diabetes, and kidney failure. Symptoms of the disease include dyspnea, rash and catarrhal signs, as well as initial low blood oxygen saturation (SpO2 <92%), leukocytosis (white blood cell count >10 × 109/L), elevated creatinine levels (>130 μmol/L) and a marked decrease in glomerular filtration rate, requiring hemodialysis. Performing organ transplant surgery in COVID-19 does not increase the risk of adverse events but could save the lives of waitlisted terminally ill patients. © 2020 Russian Transplant Society. All rights reserved.
Цитирование
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Версии
- 1. Version of Record от 2021-04-27
Метаданные
Название журнала
- Vestnik Transplantologii i Iskusstvennykh Organov
Том
- 22
Выпуск
- 3
Страницы
- 8-17
Ключевые слова
- creatinine; adult; Article; blood cell count; cardiovascular disease; coronavirus disease 2019; diabetes mellitus; dyspnea; female; glomerulus filtration rate; graft recipient; heart graft; human; kidney failure; kidney graft; laboratory test; liver graft; lung disease; major clinical study; male; multicenter study; observational study; organ transplantation; outcome assessment; prevalence; rash; risk factor
Издатель
- Russian Transplant Society
Тип документа
- journal article
Тип лицензии Creative Commons
- CC
Правовой статус документа
- Свободная лицензия
Источник
- scopus
