Статья

Recombinant tissue plasminogen activator treatment for COVID-19 associated ARDS and acute cor pulmonale

D. Kosanovic, A. Yaroshetskiy, N. Tsareva, Z. Merzhoeva, N. Trushenko, G. Nekludova, R. Schermuly, S. Avdeev,
2021

Existing literature highlights the fact that patients with COVID-19 exhibit alterations in the coagulation process and are associated with respiratory and cardiovascular diseases, including acute respiratory distress syndrome and acute cor pulmonale. In this report, we describe the effects of systemic thrombolysis on acute cor pulmonale in a patient suffering from COVID-19. We demonstrated that systemic thrombolysis successfully improved the hemodynamics of our patient and resulted in a prominent reduction in hypercapnia, alveolar dead space, and ventilatory ratio. © 2020 The Author(s)

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  • 1. Version of Record от 2021-04-27

Метаданные

Об авторах
  • D. Kosanovic
    I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation
  • A. Yaroshetskiy
    Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Giessen, Germany
  • N. Tsareva
  • Z. Merzhoeva
  • N. Trushenko
  • G. Nekludova
  • R. Schermuly
  • S. Avdeev
Название журнала
  • International Journal of Infectious Diseases
Том
  • 104
Страницы
  • 108-110
Ключевые слова
  • alteplase; atenolol; azithromycin; ceftriaxone; D dimer; enalapril; enoxaparin; ferritin; hydroxychloroquine; rosuvastatin; tocilizumab; Acinetobacter infection; adult respiratory distress syndrome; aged; Article; artificial ventilation; body temperature; cardiopulmonary hemodynamics; case report; clinical article; continuous positive airway pressure; cor pulmonale; coronavirus disease 2019; dry cough; dyspnea; echocardiography; emergency ward; fatality; ferritin blood level; fever; fibrinolytic therapy; glucose blood level; ground glass opacity; human; hypercapnia; hypertension; hypoxemia; intubation; lung artery pressure; male; mask ventilation; myalgia; nasopharyngeal swab; non-smoker; obese patient; positive pressure ventilation; respiratory failure; septic shock; thorax radiography; tomography; ventilator associated pneumonia
Издатель
  • Elsevier B.V.
Тип документа
  • journal article
Тип лицензии Creative Commons
  • CC
Правовой статус документа
  • Свободная лицензия
Источник
  • scopus