The article reflects the results of the practical implementation of measures to organize the work of the personnel of construction organizations, which were developed and implemented during the spread of the new coronavirus infection (COVID-19). According to the author, the Russian Government has chosen the right strategy to combat COVID-19, and as a result, the damage caused by coronavirus infection was less in our country than in many other countries. To develop a system of measures that have been successfully implemented at a construction enterprise, the author studied the general for all employers and special industry (for construction) regulatory documents and methodological recommendations developed by the authorities of the Russian Federation, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, the Ministry of Health of Russia, the Ministry of Construction of Russia, the Government of Moscow, The Government of the Moscow Region, the Association “All-Russian Non-State Non-Commercial Organization - the All-Russian Industry Association of Employers “National Association of Self-Regulatory Organizations Based on Membership of Persons Carrying Out Construction”, and on their basis a system of organizational and control measures was prepared and implemented into the work of the enterprise, presented in the article.