RT - journal article
SR - Electronic
T1 - Issues of diagnosis and management of patients with neuroendocrine cell hyperplasia of infancy
JF - Pediatriya - Zhurnal im G.N. Speranskogo
SP - 2020-07-01
DO - 10.24110/0031-403X-2020-99-4-78-87
A1 - Ovsyannikov, Dmitry Yuryevich
A1 - Karpenko, M. A.
A1 - Zhestkova, M. A.
A1 - Asherova, I. K.
A1 - Baychikova, A. A.
A1 - Daniel-Abu, M.
A1 - Gitinov, Sh A.
A1 - Zaitseva, S. V.
A1 - Kovalenko, I. V.
A1 - Kustova, O. V.
A1 - Malakhov, A. B.
A1 - Osmanov, I. M.
A1 - Pavlova, E. S.
A1 - Petryaykina, E. E.
A1 - Popova, V. V.
A1 - Rtishchev, A. Yu
A1 - Samitova, E. R.
A1 - Skobeev, D. A.
A1 - Starevskaya, S. V.
A1 - Talalaev, A. G.
A1 - Topilin, O. G.
A1 - Frolov, P. A.
YR - 2020
UL - https://covid19.neicon.ru/index.php/publication/4568
AB - Neuroendocrine hyperplasia of infancy (NEHI) is an interstitial lung disease (ILD) of unknown etiology, which develops in infancy and manifests as persistent tachypnea. Objective of the research: to summarize results of observations of patients with NEHI, including during the pandemic of a new coronavirus infectious disease (COVID-19). Materials and methods: clinical and follow-up observation, laboratory and instrumental examination, including lung biopsy, 52 children with NEHI aged from 21 days to 10 years. Results: NEHI more often affects boys in the first 6 months of life; can be diagnosed on the basis of pediatric ILD-syndrome detection; specific CT signs, lung biopsy. It is characterized by undulating course with increased respiratory failurec aused by acute respiratory viral infections, COVID-19; half of the patients need oxygen therapy.