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Статья
Analysis of the intricate effects of polyunsaturated fatty acids and polyphenols on inflammatory pathways in health and disease
2021
Prevention and treatment of non-communicable diseases (NCDs), including cardiovascular disease, diabetes, obesity, cancer, Alzheimer's and Parkinson's disease, arthritis, non-alcoholic fatty liver disease and various infectious diseases; lately most notably COVID-19 have been in the front line of research worldwide. Although targeting different organs, these pathologies have common biochemical impairments – redox disparity and, prominently, dysregulation of the inflammatory pathways. Research data have shown that diet components like polyphenols, poly-unsaturated fatty acids (PUFAs), fibres as well as lifestyle (fasting, physical exercise) are important factors influencing signalling pathways with a significant potential to improve metabolic homeostasis and immune cells' functions. In the present manuscript we have reviewed scientific data from recent publications regarding the beneficial cellular and molecular effects induced by dietary plant products, mainly polyphenolic compounds and PUFAs, and summarize the clinical outcomes expected from these types of interventions, in a search for effective long-term approaches to improve the immune system response. © 2020 Elsevier Ltd
Цитирование
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Версии
- 1. Version of Record от 2021-04-27
Метаданные
Название журнала
- Food and Chemical Toxicology
Том
- 143
Страницы
- -
Ключевые слова
- omega 3 fatty acid; polyphenol; polyunsaturated fatty acid; polyphenol; unsaturated fatty acid; carbohydrate diet; clinical outcome; coronavirus disease 2019; diet restriction; eating habit; health impact assessment; human; immune response; inflammatory disease; Mediterranean diet; metabolic disorder; microenvironment; nonhuman; plant product; Review; administration and dosage; animal; dietary fiber; exercise; inflammation; low carbohydrate diet; non communicable disease; physiology; Animals; Diet, Carbohydrate-Restricted; Diet, Mediterranean; Dietary Fiber; Exercise; Fatty Acids, Unsaturated; Humans; Inflammation; Noncommunicable Diseases; Polyphenols
Издатель
- Elsevier Ltd
Тип документа
- Review
Тип лицензии Creative Commons
- CC
Правовой статус документа
- Свободная лицензия
Источник
- scopus
