COVID-19 pandemic changed the setup of vascular centers. The co-existence of coronaviral infection and neurological symptoms is an important issue. On the one hand, neurological manifestations can result from acute stroke in a patient afflicted with SARS-CoV-2. On the other hand, they can be caused by the direct brain viral damage. Coronavirus damage of central neural system includes encephalitis and infection-related toxic encephalopathy. The latter can present with various manifestations (from headache to conscious disorders in severe cases). Therefore, additional diagnostic approaches and new treatment protocols are required. The paper covers important issues related to healthcare delivery for patients with neurologic symptoms in COVID-19 pandemic. © 2020 All-Russian Public Organization Antihypertensive League. All rights reserved.